Remediation and Document Management Services for Sponsor

Situation: A late stage biopharmaceutical company working on a fast-tracked Phase 3 study was providing their own document management and recently partnered with an eTMF solution provider to manage their eTMF. Due to eTMF platform constraints and lack of TMF training/awareness, the company found themselves at risk of FDA non-compliance. With over 4000 backlogged documents…

Read More

How To: File a Certified Copy (and Leave Paper Behind)

About LMK’s How-To Series LMK’s commitment to education inspires our most popular and most important service offering: TMF University. TMF University is LMK’s industry-first TMF training program, offering a wide range of courses to suit all needs; from beginners just learning to identify common regulatory documents to professionals seeking to hone their expertise.   Celebrating…

Read More

How To: How to Use E-Signatures

About LMK’s How-To Series LMK’s commitment to education inspires our most popular and most important service offering: TMF University. TMF University is LMK’s industry-first TMF training program, offering a wide range of courses to suit all needs; from beginners just learning to identify common regulatory documents to professionals seeking to hone their expertise.   Celebrating…

Read More

LMK’s TMF Mentoring & Training Services Improve International Company’s Process

Situation: A large international pharmaceutical company implemented a new centralized TMF program. As a result of the new program, the company lacked the trained resources needed to effectively manage the TMF program. LMK provided training and professional mentorship for the newly formed TMF Lead, TMF Project Manager and TMF Document Associates roles. LMK Solutions: For…

Read More

LMK’s Oversight TMF QC Process Ensures TMF Completeness

Situation: A small biotech company outsourced the data management, monitoring, and regulatory functions of their oncology program to a clinical research organization (CRO). Unfortunately, the biotech company did not have a process in place to perform oversight of the Trial Master File (TMF) throughout the duration of the study. The sponsor contracted LMK to provide Oversight Quality Control…

Read More

LMK Navigates the Process of Selecting the “Right” eTMF Solution: Saves Client $1.5M and Implements eTMF Solution 5 months Ahead of Schedule

Situation: A mid-size pharmaceutical company decided it was time to move their paper TMF into an electronic Trial Master File (eTMF) system. With so many eTMF vendors on the market and all the different functionality that these systems can perform, our client was a bit overwhelmed and requested LMK’s support with selecting an eTMF vendor.…

Read More

LMK’s eTMF Indices Quality Review Process Ensures the Highest Level of TMF Quality

Situation: LMK was contracted by a large pharmaceutical company to ensure that all of the Trial Master File (TMF) indices (ie, regulatory submission) were present for their “high-risk” studies according to each study’s specification. LMK Solutions: To verify TMF completeness, LMK resources performed a gap analysis on the electronic TMF (eTMF) processes using our customized…

Read More

LMK Remembers the 100th Anniversary of World War I

LMK Clinical Research Consulting recognizes our debt to all veterans, past and present. We acknowledge their sacrifice that ensures all Americans may share in our most important principles of freedom, justice, and liberty. These fundamental principles are the foundation of all worthwhile scientific and medical advancement. November 11th, 2018 marks the 100th year anniversary of…

Read More